Malaria is a hot button issue for many human rights activists. It is the most deadly communicable disease on earth, killing over 1 million people every year. Yet it is one of the least studied diseases. Many claim this paradox is due to the fact that virtually all deaths from malaria occur in undeveloped countries and decimate populations with no financial resources.
There are some drugs that can be used in the treatment of malaria, but over time the parasites evolve immunity to the drug, renderring them ineffective. Every ten years or so a new malaria drug must be developed. Resaerchers have attempted to develop vaccines to malaria before, but haven't been able to produce enough proteins specific to Plasmodium (the malaria causing parasite) to initiate a host reaction, until now.
Researchers at Johns Hopkins have expressed enough Pfs48/45 (a Plasmodium protein) to develop a vaccine that initiates antibody production in mice and non-human primates. Protection against malaria may be on the horizon.
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