The malaria parasite spends much of its life within human cells or within mosquitoes, making the study of single genes more difficult and time consuming than for other organisms. Therefore, my laboratory has been developing tools, such as microarrays, that allow the activity of all genes to be studied simultaneously. We are using computational methods to combine this data with other pieces of information about the genome to develop models of what genes are likely to be doing and how the genes may be regulated. If we can find proteins that are critical for the parasite’s survival, development, and pathogenesis, we may be able to find chemicals that target these proteins, leading to new drug and vaccine therapies.
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The Scripps Research Institute
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Make new connections, learn about science, share my science, learn about what other San Diegan's say about science, events