One size fits all. An ingenious idea to maximize customer base while minimizing production effort. Also remarkably effective at convincing people to pay for inferior quality merchandise that barely serves the intended purpose, if at all. Customers are willing to gamble with functionality on accessory items such as gloves or hats, but for intimate essentials like shirts and shoes they demand more tailored apparel.

So why is it that we have come to accept a…

 While the overall hospitalization rate for stroke has declined in recent years, the numbers have  jumped dramatically for patients infected with human immunodeficiency virus (HIV), suggesting they may be up to three times more likely to suffer a stroke than people uninfected by the virus that causes AIDS.…

 For the members of CineGrid, who assembled recently at the University of California, San Diego, for their fifth annual conference, experimenting with “extreme” digital media has increasingly become a finely tuned balance of “3D in support of collaboration, and collaboration in support of 3D.”…

LA JOLLA, CA – January 18, 2011 – Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for…

 LA JOLLA, CA—Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease-early-onset familial Alzheimer's-which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets. Without it, budding motor neurons misread their guidance signals and get…

 LA JOLLA, CA – January 20, 2011 – Scientists at The Scripps Research Institute have found that a known enzyme in cells protects against measles virus, likely by altering the virus’s genetic material, RNA. Cells lacking the enzyme become highly vulnerable to the virus’s destructive effects. The enzyme also protects against several other respiratory viruses, including influenza A.…

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The new detailed description of the complete HIV capsid (outer shell) will provide a roadmap for drugs that can disrupt its formation and thus prevent infection by HIV. (Graphics by Owen Pornillos, Barbie Ganser-Pornillos,…

 DARIEN, IL – Patients with obstructive sleep apnea often report that they feel like "a new person" after beginning treatment with continuous positive airway pressure therapy. A new study in the Jan. 1 issue of the journal SLEEPprovides objective evidence to support these anecdotal reports, showing that three weeks of CPAP therapy significantly reduced fatigue and increased energy in patients with OSA.…

 New research by scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences reveals that the immune system has an effective backup plan to protect the body from infection when the “master regulator” of the body’s innate immune system fails.  The study appears in the December 19 online issue of the journal Nature Immunology.…

 A multinational team of researchers led by stem cell scientists at the University of California, San Diego School of Medicine and Scripps Research Institute has documented specific genetic abnormalities that occur in human embryonic (hESC) and induced pluripotent stem cell (iPSC) lines.  Their study, “Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture” will be published in the January 7 issue of…

 LA JOLLA, CA—In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here's one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these tiny cellular factories could extend your life-an observation relevant not only to aging research but to our understanding of how cells communicate with each another.

So report…

 Babies, even those too young to talk, can understand many of the words that adults are saying – and their brains process them in a grown-up way.

Combining the cutting-edge technologies of MRI and MEG,…