The University of California, San Diego School of Medicine has received a $5.3 million grant from the National Cancer Institute to conduct and lead a first-of-its-kind, four-year clinical trial to show the effects of weight loss and increased physical activity on quality of life and on co-existing medical conditions in overweight breast cancer survivors. This trial is designed as a vanguard component of a larger study that will examine the effect of weight loss on recurrence risk for breast…

The Findings Open the Door to the Development of More Effective Therapies for Lymphomas and Leukemias



To target and attack cancerous B cells, the scientists combined two different types of molecules into one, using both new and tried-and-true technology. This image shows B-cells binding to the new compound. (Image by Mary O'Reilly.)

LA JOLLA, CA – June 7, 2010 –Scripps Research Institute scientists have discovered a new way to target and destroy a type of cancerous cell. The…

LA JOLLA, CA—For a plant, light is life. It drives everything from photosynthesis to growth and reproduction. Yet the chain of molecular events that enables light signals to control gene activity and ultimately a plant's architecture had remained in the dark. Now a team of researchers from the Salk Institute for Biological Studies and Duke University have identified the courier that gives the signal to revamp the plant's gene expression pattern after photoreceptors have been activated by…

Chemical sensors printed directly on elastic underwear waistbands retained their sensing abilities even after engineers stretched, folded and pulled at the chemical-sensing printable electrodes – sensors that could one day be incorporated into intelligent “hospital-on-a-chip” systems. This work, funded by the U.S. Office of Naval Research, is led by professor Joseph Wang, from the Department of NanoEngineering at the University of California, San Diego Jacobs School of Engineering.…

Scripps Institution of Oceanography / University of California, San Diego

Three local university research teams will receive grants and business mentoring to help further develop and commercialize clean technology research projects through a partnership between the city of San Diego, local universities and private companies.



Designed to support commercialization of clean technology innovations developed at universities, the San Diego Clean Tech Innovation…

Sanford-Burnham researchers redirect a known pain reliever to trigger death pathways in cancer cells.

LA JOLLA, Calif., June 15, 2010 – Without knowing exactly why, scientists have long observed that people who regularly take non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin have lower incidences of certain types of cancer. Now, in a study appearing in Cancer Cell on June 15, investigators at Sanford-Burnham Medical Research Institute…

Caption: The new study reveals the structure of an unusual human antibody against HIV called PG16.

LA JOLLA, CA – June 1, 2010 –In findings that contribute to efforts to design an AIDS vaccine, a team led by Scripps Research Institute scientists has determined the structure of an immune system antibody molecule that effectively acts against most strains of human immunodeficiency virus (HIV), the virus that causes AIDS.

The study, which is being published in an…

Climate change continues to drive dramatic losses in the Arctic sea ice that the polar bear calls home. As sea ice losses mount, the Arctic has become less isolated and so human activities in the area are only expected to increase over coming decades.

The San Diego Zoo’s Institute for Conservation Research, in collaboration with, and with support from Polar Bears International®, continues to delve into…

An international group of researchers has identified the genetic cause of an inherited condition that causes severe fetal abnormalities.

The work, co-led by geneticists at the UCSD Institute for Genomic Medicine, together with colleagues from…

It’s 2 a.m. on March 4, 2009. At a hotel near Kennedy Space Center, the night sky is full of stars, and so is Bill Welsh’s mind.

 

The San Diego State astronomy professor bolted awake, suddenly plagued with doubts about the computations he’d done for NASA’s Kepler space mission. The mission was to launch in less than a week and Welsh was part of its nationwide science…

 …

ImmunoCellular Therapeutics, Ltd. (OTC.BB: IMUC ), a clinical-stage biotechnology company that is developing immune based therapies for the treatment of brain and other cancers, announced today that the Company and Torrey Pines Institute for Molecular Studies in San Diego, CA have identified several peptides which can generate CD-133 specific T-cells. CD-133 is found in high abundance on…