LA JOLLA, CA – December 27, 2011 – Scientists at The Scripps Research Institute have discovered that DNA stays too tightly wound in certain brain cells of schizophrenic subjects. The findings suggest that drugs already in development for other diseases might eventually offer hope as a treatment for schizophrenia and related conditions in the elderly.
The research, now available online in the new Nature journal, Translational Psychiatry, shows the deficit is especially…
ContinueAdded by MySDScience on December 28, 2012 at 6:30am — No Comments
LA JOLLA, CA—Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people. Their findings provide new ways to predict and personalize the diagnosis and treatment of cancer.
In a paper published February 3…
Added by MySDScience on February 7, 2012 at 12:00pm — No Comments
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have identified a gene that tells cells to develop multiple cilia, tiny hair-like structures that move fluids through the lungs and brain. The finding may help scientists generate new therapies that use stem cells to replace damaged tissues in the lung and other organs.
"Cells with multiple cilia play a number of important roles, including moving fluids through the respiratory tract, brain and spinal cord," says …
ContinueAdded by MySDScience on January 11, 2012 at 12:30pm — No Comments
LA JOLLA, CA—An international team of scientists has created super-strong, high-endurance mice and worms by suppressing a natural muscle-growth inhibitor, suggesting treatments for age-related or genetics-related muscle degeneration are within reach.
The project was a collaboration between researchers at the Salk Institute for Biological Studies, and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the …
ContinueAdded by MySDScience on November 14, 2011 at 10:30am — No Comments
LA JOLLA, CA—One of the few reliable ways to extend an organism's lifespan, be it a fruit fly or a mouse, is to restrict calorie intake. Now, a new study in fruit flies is helping to explain why such minimal diets are linked to longevity and offering clues to the effects of aging on stem cell behavior.
Scientists at the Salk Institute for Biological Studies and their collaborators found that tweaking a gene known as PGC-1, which is also found in human DNA, in the intestinal stem cells…
ContinueAdded by MySDScience on November 2, 2011 at 5:00pm — 1 Comment
JUPITER, FL, October 26, 2010 — The Scripps Research Institute has been awarded a $500,000 grant by the Michael J. Fox Foundation to study a pair of genetic mutations that could lead to a new and potentially vital therapeutic target for Parkinson’s disease, a progressive and fatal neurodegenerative disorder.
Philip LoGrasso, PhD, a professor…
ContinueAdded by MySDScience on October 27, 2011 at 6:00pm — No Comments
LA JOLLA, CA—A new class of anti-inflammatory drugs may one day serve as an alternative to steroid medications and possibly help avoid the serious side effects of steroids, based on research findings at the Salk Institute for Biological Studies.
The scientists, led by Inder M. Verma, a professor in Salk's Laboratory of Genetics and…
ContinueAdded by MySDScience on October 24, 2011 at 6:00pm — No Comments
Bruce Beutler, M.D., Chair of the Department of Genetics at The Scripps Research Institute and professor and director of the Center for the Genetics of Host Defense at UT Southwestern Medical Center, has won the 2011 Nobel Prize in Physiology or Medicine.
Bestowed annually by the Royal Swedish Academy of Sciences for achievements in physics, chemistry, medicine, literature, economics, and peace, the prize recognizes individuals who, as stipulated in Alfred Nobel's will, "have…
Added by MySDScience on October 3, 2011 at 3:30pm — No Comments
LA JOLLA, CA—Ever wondered why you wake up in the morning—even when the alarm clock isn't making jarring noises? Wonder no more. Researchers at the Salk Institute for Biological Studies have identified a new component of the biological clock, a gene responsible for starting the clock from its restful state every morning.
The biological clock ramps up our metabolism early each day, initiating important physiological functions that tell our bodies that it's time to rise and shine.…
ContinueAdded by MySDScience on September 30, 2011 at 8:00am — 1 Comment
Only 17 T-R01 projects were selected throughout the country and will be supported with a total of…
ContinueAdded by MySDScience on September 29, 2011 at 8:30am — No Comments
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