MySDScience's Article (273)

Scripps Research Scientists Discover a Brain Cell Malfunction in Schizophrenia

LA JOLLA, CA – December 27, 2011 – Scientists at The Scripps Research Institute have discovered that DNA stays too tightly wound in certain brain cells of schizophrenic subjects. The findings suggest that drugs already in development for other diseases might eventually offer hope as a treatment for schizophrenia and related conditions in the elderly.

The research, now available online in the new Nature journal, Translational Psychiatry, shows the deficit is especially…

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Added by MySDScience on December 28, 2012 at 6:30am — No Comments

SDSC Supercharges its ‘Data Oasis’ Storage System

Sustained Speeds of 100 GB/s Needed to Support SDSC’s ‘Big Data’ Initiatives

The San Diego Supercomputer Center (SDSC) at the University of California, San Diego has completed the deployment of its Lustre-based Data Oasis parallel file system, with four petabytes (PB) of capacity and 100 gigabytes per second (GB/s), to handle the data-intensive needs of the center’s new …

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Added by MySDScience on June 5, 2012 at 4:30pm — No Comments

UC San Diego to Study Accelerated Aging in Schizophrenia

Researchers at the Stein Institute for Research on Aging at the University of California, San Diego have received a $4 million grant from the National Institute of Mental Health (NIMH), part of the National Institutes of Health, to study accelerated biological aging in schizophrenia.

“Schizophrenia is one of the most serious, challenging, and disabling mental illnesses,” said principal investigator Dilip V. Jeste, MD, Estelle and Edgar Levi…

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Added by MySDScience on June 5, 2012 at 4:30pm — No Comments

A Vision to Help

Engineering students design bare-bones microscope for clinics in developing world

blood cells

Photo by Treyscope Media

Students at the Jacobs School of Engineering are working to develop a cheaper, lighter, multi-function microscope that could be used in clinics in developing countries. Their prototype will be flown to Mozambique this summer and field tested at Universidade Eduardo Mondlane in the country’s capital, Maputo.

Similar microscopes…

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Added by MySDScience on June 5, 2012 at 4:30pm — No Comments

How Infectious Disease May Have Shaped Human Origins

Inactivation of two genes may have allowed escape from bacterial pathogens, researchers say

<p><em>Escherichia coli </em>bacteria, like these in a false-color scanning electron micrograph by Thomas Deerinck at UC San Diego’s National Center for Microscopy and Imaging Research, cause a variety of often life-threatening conditions, particularly among the young. Varki and colleagues suggest a genetic change 100,000 or so years ago conferred improved protection from these microbes, and likely altered human evolutionary development.</p>

Escherichia coli bacteria, like these in a false-color scanning electron micrograph by Thomas Deerinck at UC San Diego’s National Center for Microscopy and Imaging Research, cause a variety of often life-threatening conditions, particularly among the young. Varki and colleagues suggest a genetic…

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Added by MySDScience on June 4, 2012 at 6:00pm — No Comments

Rattlesnakes Strike Again in San Diego, Bites More Toxic

UC San Diego Health System Toxicologist Offers Venomous Bite Advice

Each year, approximately 8,000 Americans are bitten by venomous snakes.  On average, 800 or so bites occur annually in California, home to an abundance of snake species, but only one family is native and venomous: rattlesnakes.

“This is the time of year when we see a rise in snake bites,” said Richard Clark, MD, director of the Division of Medical Toxicology…

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Added by MySDScience on June 4, 2012 at 4:30pm — No Comments

Scripps Research Institute Study Suggests Expanding the Genetic Alphabet May Be Easier than Previously Thought

LA JOLLA, CA – June 3, 2012 ­– A new study led by scientists at The Scripps Research Institute suggests that the replication process for DNA—the genetic instructions for living organisms that is composed of four bases (C, G, A and T)—is more open to unnatural letters than had previously been thought. An expanded “DNA alphabet” could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from…

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Added by MySDScience on June 3, 2012 at 4:30pm — No Comments

San Diego Medtech Entrepreneur Peter Farrell Elected to Scripps Research Institute Board of Trustees

LA JOLLA, CA, June 1, 2012 – Peter Farrell, chairman and chief executive officer of San Diego-based ResMed, has been elected to The Scripps Research Institute’s Board of Trustees.

“We would like to offer Peter a warm welcome,” said Dick Gephardt, President/CEO of Gephardt Government Affairs and lead trustee of the Scripps Research Board of Trustees. "We are confident his contributions to the board will help foster the Institute's continued preeminence in biomedical research and…

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Added by MySDScience on June 1, 2012 at 4:30pm — No Comments

‘Fallen Star’ Opens to the Public

18th Sculpture in UC San Diego’s Stuart Collection Is Both Homey and Disorienting

Photos by Philipp Scholz Rittermann

The artist wasn’t sure it could be done. When Do Ho Suh first proposed “Fallen Star” to UC San Diego’s Stuart Collection, he “never thought it would be realized.” A cottage built from scratch and permanently joined to an existing campus building – several stories up in…

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Added by MySDScience on May 31, 2012 at 6:00pm — No Comments

Scripps Research Institute’s Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research

LA JOLLA, CA – May 31, 2012 ­– Scripps Research Institute Professor Richard A. Lerner, MD, has won a prestigious international honor, the Prince of Asturias Award for Scientific and Technical Research, according to an announcement made today by the Prince of Asturias Foundation. Lerner shares the award with British biochemist Sir Gregory Winter, PhD.

Sometimes called the “Spanish Nobel Prize,” the Prince of Asturias Award for Scientific and Technical Research is bestowed for findings…

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Added by MySDScience on May 31, 2012 at 4:30pm — No Comments

Defense Funding Awarded to Four Scripps Oceanography Researchers

Scripps Institution of Oceanography / University of California, San Diego

Four Scripps Institution of Oceanography at UC San Diego, researchers will receive Navy funding to acquire and deploy instruments in support of studies ranging from coastal oceanography to deep-ocean acoustics. The awards mark the continuation of a partnership between Scripps and the Navy that predates World War II.

The Department of Defense (DoD) awarded a total of…

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Added by MySDScience on May 29, 2012 at 6:00pm — No Comments

Study Reveals How the World's First Drug for Amyloid Disease Works

LA JOLLA, CA – May 29, 2012 – Scientists from The Scripps Research Institute and Pfizer Inc. have published a new study showing how a new drug called tafamidis (Vyndaqel®) works. Tafamidis, approved for use in Europe and currently under review by the US Food and Drug Administration (FDA), is the first medication approved by a major regulatory agency to treat an amyloid disease, a class of conditions that include Alzheimer’s.

Tafamidis treats a deadly nerve disease caused by…

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Added by MySDScience on May 29, 2012 at 4:30pm — No Comments

Study Reveals How the World's First Drug for Amyloid Disease Works

LA JOLLA, CA – May 29, 2012 – Scientists from The Scripps Research Institute and Pfizer Inc. have published a new study showing how a new drug called tafamidis (Vyndaqel®) works. Tafamidis, approved for use in Europe and currently under review by the US Food and Drug Administration (FDA), is the first medication approved by a major regulatory agency to treat an amyloid disease, a class of conditions that include Alzheimer’s.

Tafamidis treats a deadly nerve disease caused by…

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Added by MySDScience on May 29, 2012 at 4:30pm — No Comments

UC San Diego Researchers Receive New CIRM Funding

Stem cell grants covers heart failure, Alzheimer’s disease, ALS and spinal cord injuries

Five scientists from the University of California, San Diego and its School of Medicine have been awarded almost $12 million in new grants from the California Institute for Regenerative Medicine (CIRM) to conduct stem cell-based research into regenerating spinal cord injuries, repairing gene mutations that cause amyotrophic lateral sclerosis and…

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Added by MySDScience on May 25, 2012 at 6:00pm — No Comments

Exotic particles, chilled and trapped, form giant matter wave

Physicists have trapped and cooled exotic particles called excitons so effectively that they condensed and cohered to form a giant matter wave.

This feat will allow scientists to better study the physical properties of excitons, which exist only fleetingly yet offer promising applications as diverse as efficient harvesting of solar energy and ultrafast computing.

“The realization of the exciton condensate in a trap opens the opportunity…

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Added by MySDScience on May 24, 2012 at 6:00pm — No Comments

SDSC to Host “Summer Institute” Supercomputer Workshop August 6-10

Applicants Asked to Apply by June 8

San Diego Supercomputer Center. Photo: Alan Decker

The San Diego Supercomputer Center (SDSC) at the University of California, San Diego, is expanding upon its successful Gordon Summer Institute program to include both its Gordon andTrestles supercomputers, with participants invited to focus on specific challenges in their areas of…

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Added by MySDScience on May 24, 2012 at 6:00pm — No Comments

SDSC to Host Summer Institute for Geosciences August 6-10

Applicants Asked to Apply by June 15

The San Diego Supercomputer Center (SDSC) at the University of California, San Diego, will host its ninth annual Cyberinfrastructure Summer Institute for Geoscientists (CSIG’12) August 6-10. Since 2004, CSIG has been funded each year by a grant from the Earth Science Division (EAR) of the National Science Foundation (NSF).

The theme for CSIG’12 is…

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Added by MySDScience on May 24, 2012 at 6:00pm — No Comments

Nuisance Seaweed Found to Produce Compounds with Biomedical Potential

Scripps-led analysis of tiny marine organisms indicates early promise in areas ranging from inflammation to skin conditions

Darkly colored cyanobacteria overtake a Hawaiian coral reef. Photo credit: Jennifer Smith

A seaweed considered a threat to the healthy growth of coral reefs in Hawaii may possess the ability to produce substances that could one day treat human diseases, a new study…

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Added by MySDScience on May 24, 2012 at 6:00pm — No Comments

UC San Diego Receives $7 Million from DOD for Innovative Neural Research

An interdisciplinary team of scientists at UC San Diego composed of physicists, biologists, chemists, bioengineers and psychologists has received a five-year, $7 million grant from the U.S. Department of Defense to investigate the dynamic principles of collective brain activity.

The innovative research effort, which is being funded by the Office of Naval Research under the Defense Department’s MultiUniversity Research Initiative, or MURI, will…

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Added by MySDScience on May 24, 2012 at 6:00pm — No Comments

Commonly Used Pesticide Turns Honey Bees into ‘Picky Eaters’

Biologists at UC San Diego have discovered that a small dose of a commonly used crop pesticide turns honey bees into “picky eaters” and affects their ability to recruit their nestmates to otherwise good sources of food.

The results of their experiments, detailed in this week’s issue of the Journal of Experimental Biology, have implications for what pesticides should be applied to bee-pollinated crops and shed light on one of the main…

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Added by MySDScience on May 23, 2012 at 6:00pm — No Comments

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