Zebrafish model of atherosclerosis.
A study using genetically modified zebrafish to visualize early events involved in development of human atherosclerosis describes an efficient model – one that the researchers say offers many applications for testing the potential effectiveness of new antioxidant and dietary therapies.
The research, led by scientists from the University of…
Added by MySDScience on November 21, 2011 at 12:00pm — No Comments
The trouble with most anti-cancer therapies is that they are lethal to most cells in the body, not just cancer cells. As a result, patients experience side effects like nausea, increased susceptibility to infection, and increased risk of developing secondary cancers later in life. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) are developing techniques to deliver cancer drugs directly to tumors, increasing their effectiveness and decreasing collateral damage. In…
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LA JOLLA, CA – November 20, 2011 – Scientists from The Scripps Research Institute and the US Army’s Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus and one of the most dangerous human pathogens.
“We suspect that we’ve found a key spot for neutralizing ebolaviruses,” said Scripps…
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LA JOLLA, CA and ARMONK, NY, November 18, 2011 - IBM's Watson computing system broke new ground earlier this year when it defeated two celebrated human competitors on the Jeopardy! game show. Now, The Scripps Research Institute is hoping to do something equally novel but more critical to human health with part of the prize money from that tournament: Find a cure for drug-resistant malaria. And it's asking for the public's help.
To that end, Scripps Research and IBM (NYSE: IBM) are…
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The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body’s response to healing skin wounds, a serious problem in diabetics and the elderly.
That’s the conclusion of biologists at the University of…
Added by MySDScience on November 17, 2011 at 11:00am — 1 Comment
LA JOLLA, Calif., November 17, 2011 – Mitochondria are often called cellular “powerhouses” because they convert nutrients into energy. But these tiny structures also help determine cellular lifespan. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) are now discovering how mitochondria alternate between duplicating and fragmenting and how these events help cells adapt to diverse physiological conditions. In a paper published November 18…
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LA JOLLA, CA—The Salk Institute is pleased to announce the appointment of five faculty members to be recipients of endowed chairs established by philanthropic leaders in support of scientific research.
The creation of three new chairs and the rededication of two existing chairs is a testament to the strong commitment of private donors who support the Salk Institute and its groundbreaking research. These significant endowments will provide crucial resources to support the laboratories…
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LA JOLLA, CA – November 17, 2011 - A international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease.
In a study published…
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MRI study finds genetic basis of brain development largely similar in mice and humans
Color-coded representations of human and mouse brains show similarities in cortical functional organization, with some variance according to species-specific needs. F/M indicates the frontal/motor cortex; S1, primary somatosensory cortex; A1, auditory cortex and V1, visual cortex.
A new study using…
Added by MySDScience on November 16, 2011 at 10:30am — No Comments
Trestles, a new supercomputer using flash-based memory and launched earlier this year by the San Diego Supercomputer Center (SDSC) at the University of California, San Diego, has made this year’s Graph500 list, a new ranking that measures how well supercomputers handle data-intensive challenges.
Based on runs using less than half of its overall compute…
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LA JOLLA, CA—An international team of scientists has created super-strong, high-endurance mice and worms by suppressing a natural muscle-growth inhibitor, suggesting treatments for age-related or genetics-related muscle degeneration are within reach.
The project was a collaboration between researchers at the Salk Institute for Biological Studies, and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the …
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A novel study involving fruit flies and mice has allowed biologists to identify two critical genes responsible for congenital heart defects in individuals with Down syndrome, a major cause of infant mortality and death in people born with this genetic disorder.
In a paper published in the November 3 issue of the open access journalPLoS Genetics, researchers from UC San Diego, the Sanford-Burnham Medical Research Institute in La Jolla, Calif., and the University of Utah report…
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