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Starving Inflammatory Immune Cells Slows Damage Caused by Multiple Sclerosis



nerve cell
Nerve cell with protective layers of myelin.

In a paper published today in the journal Scientific Reports, a pair of researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease…

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Added by ScholarNexus, LLC on September 2, 2011 at 9:30am — No Comments

UC San Diego Health System Opens Comprehensive Liver Clinic in Nevada

Patients in Nevada seeking care for liver disease may now access the university-level expertise of UC San Diego Health System’s Center for Hepatobiliary Disease and Abdominal Transplantation (CHAT). Led by Robert Gish, MD, world-renowned hepatologist, patients may benefit by having access to a full spectrum of liver care, from diagnostics and testing to novel therapies and clinical trials not found anywhere else in the state. Located at 3033W. Horizon Ridge Parkway, Suite 101, in the city of…

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Added by ScholarNexus, LLC on August 25, 2011 at 8:00am — No Comments

Alaskan family keeps pioneering spirit alive donating $1.6 million to Salk Institute

Salk Institute for Biological Studies



August 19, 2011

LA JOLLA, CA—The Salk Institute for Biological Studies today announced a generous $1.6 million dollar gift from the estate of Henry and Lottie O'Neal of Anchorage, Alaska. Their substantial donation will help continue the pioneering research conducted at the Salk Institute.

Henry and Lottie O'Neal, childhood sweethearts married 51 years,…

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Added by ScholarNexus, LLC on August 24, 2011 at 4:53pm — No Comments

Bestselling Author Stedman Graham to Speak at UC San Diego OASIS Summer Bridge Graduation Aug. 25





Graham
Stedman Graham will be the keynote speaker at the OASIS Summer Bridge graduation.

Stedman Graham teaches that in the 21st century one’s talent and skills above all else will define one’s value. At the University of California, San Diego, 140 high-achieving, incoming students from underserved high…

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Added by ScholarNexus, LLC on August 24, 2011 at 8:00am — No Comments

Qualcomm and Renaissance Academy Launch Project Using 3G Mobile Broadband to Help High School Correspondence Students Earn Diplomas

 – Juli 27, 2011 – Qualcomm Incorporated (NASDAQ: QCOM), through its Wireless ReachTM initiative, and Renaissance Academy Incorporated, a private correspondence high school in Daigo-cho, Ibaraki, today announced the launch of the 3G Smartphone x Digital Textbook project to help high school dropouts, habitual absentees and students seeking vocational training earn diplomas.

In Japan, the unemployment rate for high school dropouts…

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Added by ScholarNexus, LLC on August 3, 2011 at 7:30am — No Comments

"Mirroring" Might Reflect Badly on You

Not Always Smart to Mimic a Person's Body Language, UC San Diego Study Shows

July 28, 2011

Inga Kiderra

 

Winkielman Video
Excerpt from one of the…
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Added by ScholarNexus, LLC on July 29, 2011 at 7:30am — No Comments

UCSD News: Chemobath For Colon Cancer Evaluated At UC San Diego Moores Cancer Center

 

Blood Cells
Debbie Soldano, RN, BSN, OCN and Andrew Lowy, MD

As part of a multicenter clinical trial, surgical oncologists at UC San Diego Moores Cancer Center are comparing the effectiveness of standard chemotherapy to a tri-modality approach to halt advanced colon cancers. The objective is to determine if there…

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Added by ScholarNexus, LLC on June 8, 2011 at 12:00pm — No Comments

Blood Simpler

UCSD researchers parse the origins of hematopoietic stem cells:

Researchers at the University of California, San Diego School of Medicine have identified a gene and a novel signaling pathway, both critical for making the first hematopoietic stem cells (HSCs) in developing vertebrate embryos. The discovery has implications for developing stem cell-based therapies for diseases like leukemia and congenital blood disorders.

HSCs are multipotent stem cells that give…

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Added by ScholarNexus, LLC on June 8, 2011 at 12:00pm — No Comments

Popular San Diego Beach Sees Significant Reduction in Water Pollution from Land

 

Storm water that falls on the grounds of Scripps Institution of Oceanography passes through an innovative water-pollution-control system, including these two inconspicuous semicircular "media filters" to remove pollutants before the water enters the ocean. Credit: Kimberly O'Connell, UCSD.

A…

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Added by ScholarNexus, LLC on June 8, 2011 at 8:00am — No Comments

Glioblastoma’s Skeletons in the Closet

Pancreatic cells from a mouse. Ductal cancer cells are stained red and the Id3 protein is shown in green. (Image courtesy of the Itkin-Ansari lab)…

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Added by ScholarNexus, LLC on June 6, 2011 at 9:00am — No Comments

Personalized Medicine World Conference 2011

 One size fits all. An ingenious idea to maximize customer base while minimizing production effort. Also remarkably effective at convincing people to pay for inferior quality merchandise that barely serves the intended purpose, if at all. Customers are willing to gamble with functionality on accessory items such as gloves or hats, but for intimate essentials like shirts and shoes they demand more tailored apparel.

So why is it that we have come to accept a…

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Added by ScholarNexus, LLC on January 25, 2011 at 11:28am — No Comments

Stroke Rate Rises for Patients with HIV Infection

 While the overall hospitalization rate for stroke has declined in recent years, the numbers have  jumped dramatically for patients infected with human immunodeficiency virus (HIV), suggesting they may be up to three times more likely to suffer a stroke than people uninfected by the virus that causes AIDS.…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:54pm — No Comments

CineGrid Takes Digital Cinema Into Next Dimension

 For the members of CineGrid, who assembled recently at the University of California, San Diego, for their fifth annual conference, experimenting with “extreme” digital media has increasingly become a finely tuned balance of “3D in support of collaboration, and collaboration in support of 3D.”…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:53pm — No Comments

Scripps Research Team Creates New Synthetic Compound with HIV-Fighting Promise

 

LA JOLLA, CA – January 18, 2011 – Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:52pm — No Comments

Unlocking the secret(ase) of building neural circuits

 LA JOLLA, CA—Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease-early-onset familial Alzheimer's-which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets. Without it, budding motor neurons misread their guidance signals and get…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:50pm — No Comments

Scripps Research Scientists Find Measles’ Natural Nemesis

 LA JOLLA, CA – January 20, 2011 – Scientists at The Scripps Research Institute have found that a known enzyme in cells protects against measles virus, likely by altering the virus’s genetic material, RNA. Cells lacking the enzyme become highly vulnerable to the virus’s destructive effects. The enzyme also protects against several other respiratory viruses, including influenza A.…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:47pm — No Comments

Scripps Research and University of Virginia Scientists Reveal Complete Structure of HIV’s Outer Shel

 Short caption: 

The new detailed description of the complete HIV capsid (outer shell) will provide a roadmap for drugs that can disrupt its formation and thus prevent infection by HIV. (Graphics by Owen Pornillos, Barbie Ganser-Pornillos,…

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Added by ScholarNexus, LLC on January 23, 2011 at 10:45pm — No Comments

Study shows that CPAP therapy reduces fatigue, increases energy in patients with sleep apnea

 DARIEN, IL – Patients with obstructive sleep apnea often report that they feel like "a new person" after beginning treatment with continuous positive airway pressure therapy. A new study in the Jan. 1 issue of the journal SLEEPprovides objective evidence to support these anecdotal reports, showing that three weeks of CPAP therapy significantly reduced fatigue and increased energy in patients with OSA.…

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Added by ScholarNexus, LLC on January 18, 2011 at 1:02pm — No Comments

Researchers Discover Human Immune System Has Emergency Backup Plan

 New research by scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences reveals that the immune system has an effective backup plan to protect the body from infection when the “master regulator” of the body’s innate immune system fails.  The study appears in the December 19 online issue of the journal Nature Immunology.…

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Added by ScholarNexus, LLC on January 18, 2011 at 12:59am — No Comments

Genetic Abnormalities Identified in Pluripotent Stem Cell Lines

 A multinational team of researchers led by stem cell scientists at the University of California, San Diego School of Medicine and Scripps Research Institute has documented specific genetic abnormalities that occur in human embryonic (hESC) and induced pluripotent stem cell (iPSC) lines.  Their study, “Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture” will be published in the January 7 issue of…

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Added by ScholarNexus, LLC on January 18, 2011 at 12:58am — No Comments

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